What was the major effect of the plague introduced to Europe from Asia in the 14th century?

The major effect of the plague introduced to Europe from Asia in the 14th century was a significant reduction in the population, estimated to be about one third of the total population. This catastrophic loss of life had profound and far-reaching consequences for European society. The decrease in population led to a shortage of labor, which in turn resulted in higher wages for workers and changes in social structure. As labor became more valuable, serfs and peasants found opportunities for greater mobility and improved living conditions.

The dramatic population decline also spurred economic shifts, as areas that had previously depended on a large labor force were faced with new economic realities. This period saw changes in agriculture, a shift towards more trade in commodities, and even fostered an environment for social upheaval and movements seeking reform.

While it's true that the plague affected trade and the power dynamics of the Church, the immediate and most impactful consequence was indeed the staggering loss of life, which reshaped the very fabric of European society during the late medieval period.